We particularly recommend Luxury Family Hotels for accommodating families, for example, The Ickworth in Suffolk, where a 'large double' can accommodate 2 adults and up to 3 children, in luxurious yet very child friendly surroundings.
Take a look at their 5 Luxury Family Hotels
Other options for 2 adults and 3 children include
Natural Retreats lodges near Richmond, or
The Rosevine on the Roseland Peninsula in Cornwall offering family apartments and suites.
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Active hotels for great value hotels all over the UK.